"Within the pages of Beat Your A-Fib, Dr.
This is not an easy thing to do, but you have been very, very successful at it." You managed to combine an encyclopedic compilation of information with the simplicity of presentation that enhances the delivery of the information to the reader. She loves it and finds it very useful to help her in dealing with atrial fibrillation." "Dear Steve, I saw a patient this morning with your book and highlights throughout. Professor of Cardiology, Haut-Lévêque Hospital, Bordeaux, France I certainly recommend it for patients who want to know more about atrial fibrillation than what they will learn from doctors." "This book is incredibly complete and easy-to-understand for anybody. "If I had 10 years ago, it would have saved me 8 years of hell.” All patients were followed until death or at least 1 month.Ĩ9% of 90 patients experienced a full reversal of the effect of Pradaxa within 4 hours of administration.Doctors & patients are saying about 'Beat Your A-Fib'. The treatment was given to two groups of patients Group A, patients with serious bleeding, and Group B, patients who required an urgent procedure. The study treatment consists of 2 infusions of 2.5 g IV Praxbind given no more than 15 mins apart. Researchers plan to recruit 300 patients in 400 centers in 38 countries. The RE-VERSE AD trial is an ongoing multicenter, prospective cohort study that looks at patients who are chronic users of Pradaxa. There was an immediate reduction (within minutes) of the effect of Pradaxa after administration of 5 g of Praxbind. Praxbind was studied in three randomized trials in 283 healthy volunteers taking Pradaxa. The FDA granted accelerated approval for Praxbind to be used in patients taking Pradaxa who need a reversal of its effects for emergency surgical procedures or life-threatening or uncontrolled bleeding. This prevents Pradaxa from blocking thrombin so the body can resume its normal clotting mechanism. Praxbind is a monoclonal antibody fragment that binds Pradaxa 350 times more strongly than thrombin. Pradaxa works by binding thrombin, the blood’s natural clotting agent, thus preventing clots from forming. Praxbind ( idarucizumab ) is an injectable drug that reverses the anticoagulation (blood thinning) effect of Pradaxa (dabigatran). What is Praxbind and its mechanism of action? Medication Class: humanized monoclonal antibody fragment
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